ABSTRACT The objective of the research was to evaluate the potential in bird tourism for ecotourism development in the Tingo María National Park (PNTM). The type of research was field, descriptive correlational level, non-experimental design, transectional. The unit of analysis were the many national, local and foreign tourists over 18 years old; a questionnaire was used to collect data, subject to reliability using Cronbach's alpha, with a sample of 383 visitors. The hypothesis test between avitourism and ecotourism development indicates a bilateral significance of 0.000, this being less than 0.05, in this sense the research hypothesis is approved; since a Spearman correlation coefficient of 0.538 is observed, this being moderate. It is concluded that if there is an adequate level of ecotourism development in the Tingo María National Park, the avitourism represents an alternative conservation because it can be carried out in protected areas, allowing the coexistence of the space dedicated to conservation and the human population settled in said space.

RESUMEN La investigación tuvo como objetivo evaluar el potencial en Aviturismo para el desarrollo ecoturístico en el Parque Nacional Tingo María (PNTM). El tipo de investigación fue de campo, nivel descriptivo correlacional, diseño no experimental, transeccional. La unidad de análisis fueron los turistas tantos nacionales, locales y extranjeros mayores de 18 años; para la recolección de datos se utilizó un cuestionario, sometido a confiabilidad mediante alfa de Cronbach, con una muestra de 383 visitantes. La prueba de hipótesis entre el aviturismo y el desarrollo ecoturístico indica una significancia bilateral 0,000 siendo este menor al 0.05, en tal sentido se aprueba la hipótesis de investigación; ya que se observa un coeficiente de correlación de Spearman de 0,538 siendo esta moderada. Se concluye que si existe un adecuado nivel de desarrollo ecoturístico en el parque Nacional Tingo María ante lo cual el aviturismo representa una alternativa de conservación pues puede llevarse a cabo en áreas protegidas, permitiendo la convivencia del espacio destinado a la conservación y de la población humana asentada en dicho espacio.

RESUMO Objetivos Os objetivos deste estudo foram avaliar a prevalência e a gravidade da fluorose dentária e avaliar o impacto da fluorose dentária na qualidade de vida relacionada à saúde bucal (QVRSB) de crianças residentes em duas cidades peruanas com diferentes níveis de flúor de água. Métodos Uma amostra de 292 crianças entre 11 e 14 anos de idade e ambos os sexos foram selecionada nas escolas públicas e privadas de ensino fundamental nas duas cidades. O exame oral clínico foi realizado utilizando-se o índice de Dean para avaliar a prevalência e a gravidade da fluorose dentária e o Questionário de Percepção Infantil 11-14 (CPQ 11-14) para avaliar a associação entre fluorose dentária e QVRSB. Resultados A prevalência de fluorose dentária foi de 75% e o escore moderado foi o mais frequente (36%). As duas cidades têm baixo nível socioeconômico e predominam as crianças de escolas públicas (74%). Não houve impacto da fluorose na QVRSB. É possível que os adolescentes que vivem em um contexto social em que a aparência dentária seja muito semelhante entre as pessoas tenham um senso de identidade diferente de outras sociedades, o que pode influenciar em sua percepção de QVRSB. Conclusão Embora a prevalência de fluorose dentária tenha sido muito alta, não teve impacto na QVRSB.

ABSTRACT Objectives The aims of this study were to evaluate the prevalence and severity of dental fluorosis and to assess the impact of dental fluorosis on oral health related quality of life (OHRQoL) of children living in two Peruvian towns with different water fluoride levels. Methods A sample of 292 children between 11 and 14 years of age and both genders were selected among public and private primary schools in the 2 towns. Clinical oral examination was carried out using Dean’s index to assess the prevalence and severity of dental fluorosis and the Child Perceptions Questionnaire 11-14 (CPQ 11-14) was used to evaluate the association between dental fluorosis and OHRQoL. Results Dental fluorosis prevalence was 75% and the moderate score was the most frequent (36%). The two towns have a low socioeconomic level and children from public schools predominate (74%). There was no impact of fluorosis on OHRQoL. It is possible that adolescents living in a context with very similar dental appearance of their peers build a sense of identity different than other populations, which can influence in their OHRQoL perception. Conclusions Even though dental fluorosis prevalence was very high it did not have impact on OHRQoL.

ABSTRACT Objective Improve distribution of etiological treatment of Chagas disease by identifying barriers to the decentralization of treatment to the first level of care in Argentina. Methods A qualitative, exploratory, and descriptive study was conducted using semi-structured interviews of key actors belonging to the National Chagas Program and members of health teams at the first level of care, for the purpose of identifying barriers to diagnosis and treatment of Chagas disease at different levels (administrative, health agents, and community) that could affect a decentralized distribution strategy. Additionally, pilot decentralization was instituted in 10 primary health care centers in an Argentine province. Results Semi-structured interviews were conducted with 22 program heads and health professionals. Principal obstacles found were lack of systematic case-finding, poor coordination among levels of care and health system actors, lack of health team training on treatment, patient monitoring, and patient-related barriers. A pilot decentralization program was carried out and strategies were evaluated to optimize large-scale intervention. Conclusions The results made it possible to improve implementation of the plan to decentralize treatment through better inter-program coordination, capitalization on existing monitoring and communication tools, and sensitization of health teams. Furthermore, recommendations were developed to improve diagnosis and treatment of Chagas disease.

RESUMEN Objetivo Mejorar la distribución del tratamiento etiológico para la enfermedad de Chagas mediante la identificación de barreras para su descentralización al primer nivel de atención en Argentina. Métodos Se llevó a cabo un estudio cualitativo, de carácter exploratorio y descriptivo, en base a entrevistas semiestructuradas a actores clave pertenecientes al Programa Nacional de Chagas y miembros de los equipos de salud del primer nivel de atención con el objetivo de identificar barreras para el diagnóstico y tratamiento de la enfermedad de Chagas en diferentes niveles (administrativo, efectores de salud y comunidad) que podrían afectar una estrategia descentralizada de distribución. Además, se implementó un piloto de descentralización en diez centros de atención primaria en una provincia argentina. Resultados Se realizaron 22 entrevistas semiestructuradas con responsables de programas y profesionales de la salud. Los principales obstáculos hallados fueron la falta de búsqueda sistemática de casos, la poca articulación entre los niveles de atención y los actores del sistema de salud, la falta de capacitación del equipo de salud respecto al tratamiento, el seguimiento de los pacientes y las barreras asociadas a los pacientes. Se llevó a cabo un programa piloto de descentralización y se evaluaron estrategias para optimizar la intervención a gran escala. Conclusiones Los resultados permitieron mejorar la implementación del plan de descentralización del tratamiento a través de una mejor articulación interprogramática, la capitalización de herramientas de monitoreo y de comunicación ya existentes, y la sensibilización de los equipos de salud. Además, se formularon recomendaciones tendientes a mejorar el diagnóstico y el tratamiento de la enfermedad de Chagas.

Introduction: studies on Maytenus trees comprising forsskaoliana, krukovii, and ilicifolia species showed depressing effects on the blood pressure and the heart rate. Objectives: to experimentally analyze the effects of Maytenus macrocarpa leaves on the heart rate, the electrocardiographic patterns, the respiratory rate, and the temperature. Method: this study was exploratory, analytical, and experimental. Albino rats were grouped in 9 groups of 8 rats each. Group 1 (control: Halatal), group 2 (placebo: distillated water), group 3 (adrenaline), group 4 (atropine), group 5 (acetylcholine), group 6 (propranolol), group 7 (500 mg/kg chuchuhuasi), group 8 (1 000 mg/kg chuchuhuasi), and group 9 (1 500 mg/kg chuchuhuasi). The rectal temperature was measured with a mercury thermometer, whereas the direct count allowed measuring the respiratory frequency. The polygraph registered electrocardiogram and heart rate as well. The MATLAB program analyzed data from the electrocardiogram. The statistic validation was performed with ANOVA, Tuckey, Wilcoxon, and Shapiro-Wilk tests. Results: Maytenus macrocarpa showed depressing effects on the cardiac frequency, being more effective at 1 500 mg/kg doses (average 308.6 ppm), higher negative inotropic effect at 1 500 mg/kg doses (average P wave 0.08300 mv, average R wave 0.1539 mV). Severe bradypnea was shown at 1 500 mg/kg doses (average RF 51.6 rpm), as well as hypothermia (average T° 31.84 °C). Conclusion: Maytenus macrocarpa demonstrated bradycardic as well as depressing effects on respiratory frequency and body temperature.

Introducción: estudios de árboles del género Maytenus, especies forsskaoliana, ilicifolia y krukovii revelan efectos depresores a nivel cardiovascular sobre la presión arterial y frecuencia cardiaca. Objetivos: analizar experimentalmente los efectos de las hojas de Maytenus macrocarpa "chuchuhuasi" sobre la frecuencia cardiaca, patrones electrocardiográficos, frecuencia respiratoria, y temperatura. Métodos: investigación de tipo exploratorio, analítico y experimental. Se utilizaron ratas albinas en 9 grupos de 8 ratas. Grupo 1 (control: Halatal), grupo 2 (placebo: agua destilada), grupo 3 (adrenalina), grupo 4 (atropina), grupo 5 (acetilcolina), grupo 6 (propranolol), grupo 7 (chuchuhuasi 500 mg/kg), grupo 8 (chuchuhuasi 1 000 mg/kg) y grupo 9 (chuchuhuasi 1 500 mg/kg). La temperatura rectal se midió con termómetro de mercurio, la frecuencia respiratoria, por conteo directo; el electrocardiograma y la frecuencia cardiaca, mediante el uso de polígrafo. El programa MATLAB se utilizó para analizar los datos obtenidos en el electrocardiograma. Para la validación estadística se usó la prueba de ANOVA, pruebas de Tuckey, Wilconxon y Shapiro-Wilk. Resultados: Maytenus macrocarpa mostró mayor actividad depresora sobre la frecuencia cardiaca (promedio 308,6 ppm), mayor efecto inotrópico negativo (promedio onda P: 0,08300 mv, promedio onda R: 0,1539 mv), marcada bradipnea (promedio 51,6 rpm) e hipotermia (promedio: 31,84 °C) a dosis de 1 500 mg/kg. Conclusiones: Maytenus macrocarpa demostró efecto bradicardizante, depresor de la frecuencia respiratoria y la temperatura corporal.